发明名称 |
FARMACEUTISCH PREPARAAT MET ANTIBACTERIELE WERKING, ALSMEDE 7BETA-(2-(4-ALKYL-2,3-DIOXOPIPERAZINE-1-YLCARBONYLAMINO)ACETYLAMINO)-3-(GESUBSTITUEERD METHYL)-3-CEFEM-4-CARBONZUUR DERIVAAT. |
摘要 |
<p>A 7 alpha -methoxycephalosporin represented by the general formula: <IMAGE> wherein R1 represents a hydrogen atom or a carboxyl-protecting group; R2 represents an organic group linked to the carbon atom through an oxygen or sulfur atom; R3 represents a lower alkyl group; n is 0, 1 or 2; A represents a hydrogen atom or a substituted or unsubstituted alkyl group; and B represents a substituted or unsubstituted alkyl, cycloalkyl, cycloalkenyl, cycloalkadienyl or heterocyclic group, and a salt thereof. These compounds have a broad antibacterial spectrum, high resistance to beta -lactamase produced from bacteria, and an effective antibacterial activity against clinical isolates of bacteria.</p> |
申请公布号 |
NL180511(C) |
申请公布日期 |
1987.03.02 |
申请号 |
NL19780007806 |
申请日期 |
1978.07.21 |
申请人 |
TOYAMA CHEMICAL CO., LTD. TE TOKIO, JAPAN. |
发明人 |
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分类号 |
C07D295/20;C07D501/24;C07D501/34;C07D501/36;C07D501/57;(IPC1-7):C07D501/57;A61K31/545 |
主分类号 |
C07D295/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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