摘要 |
<p>steroids with physiological activity and for use as intermediates in synthesis of sex steroids, are made by (A) mixing a 11 beta-hydroxy steroid of androstane or pregnane series with anhydrous SO2 in presence of an organic base, e.g. pyridine, under anhydrous conditions of ambient temp.; and (b) treating the mixt. with chlorine, bromine, iodine or sulphuryl bromide or iodide, at 30 deg.C max.</p> |