发明名称 |
Method and system for detection of complement pathway activation |
摘要 |
A method and system for detecting and preferably measuring the presence of an activated complement complex in a sample is discussed. The presence of such an activated complex is indicative of complement pathway activation and includes a first complement component and a second complement component. The method uses a first binding agent specific to the first complement component and a second binding agent specific to the second complement component which when bound with the complex forms an aggregate. The second specific binding agent includes a label whose presence is used to detect and measure the amount of aggregate and therefore activated complex in a sample. An assay system and aggregate for use in an assay system are also discussed.
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申请公布号 |
US4642284(A) |
申请公布日期 |
1987.02.10 |
申请号 |
US19830503705 |
申请日期 |
1983.06.13 |
申请人 |
SCRIPPS CLINIC AND RESEARCH FOUNDATION |
发明人 |
COOPER, NEIL;MAYES, JAMES T. |
分类号 |
G01N33/53;C12Q1/00;G01N33/536;G01N33/537;G01N33/564;(IPC1-7):G01N33/563 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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