发明名称
摘要 PURPOSE:A preventive and curing medicine for bacteria infectious disease effective against both resistant and nonresistant bacteria, comprising apotransferrin derived from human blood serum and plasma as a main component. CONSTITUTION:Comprising apotrasferrin, glycoprotein existing both in human blood serum and plasma as a main component. The compound contains about 5.5wt% of sugar, belongs to beta-globuline electrophoretically and has a molecular weight of 70,000-90,000. It prevents the intoxication action caused by an excess of iron ion in the blood serum and acts as a carrier to provide the body with iron ions in the form of nontoxicity depending upon the seversible reaction between the compound and transferrin combined with iron. By administration of the compound, free iron to be given to a iron-requiring bacteria (e.g., bascillus subtilis, Staphylococcus, dysentery bacillus, a tubercle facillus, Pseudomonas aeruginosa) is taken to exhibit a preventive and curing effect.
申请公布号 JPS623813(B2) 申请公布日期 1987.01.27
申请号 JP19790027564 申请日期 1979.03.09
申请人 GREEN CROSS CORP 发明人 DOI TAKUJI;NAKAJIMA TSUNETAKA;FUNAKOSHI SATORU
分类号 A61K35/14;A61K35/16;A61K38/16;A61P31/04 主分类号 A61K35/14
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