发明名称 APPLICATION OF 10-HYDROXY-10,11-DIHYDROCARBAMAZEPINE DERIVATIVES FOR TREATMENT OF AFFECTIVE DISORDERS
摘要 FIELD: medicine. ^ SUBSTANCE: inventions refer to psychiatry, to treatment of the disease as specified: bipolar disorder, psychotic states as maniacal syndrome or schizophrenia, or redundant emotional mobility wherein behavioural stabilisation is desired. The present inventions concern compounds of formula I where R1 represents hydrogen or C1-C3alkylcarbonyl or its pharmaceutically acceptable salt applied to treat the specified diseases, and form a pharmaceutical composition to treat the specified diseases; a combination additionally containing at least one compound, chosen from the group including lithium, divalproex, standard antipsychotic agents, atypical antipsychotic agents, lamotrigine and antidepressants; and a commercial package including the specified combination with prescribing information. ^ EFFECT: more effective treatment of the disease as specified: bipolar disorder, psychotic states as maniacal syndrome or schizophrenia, or redundant emotional mobility. ^ 21 cl, 4 ex
申请公布号 RU2367440(C2) 申请公布日期 2009.09.20
申请号 RU20050133665 申请日期 2004.04.01
申请人 NOVARTIS AG 发明人 MARTENII FERENTS;SHMUTTS MARKUS;TSEKHNER SHTEFANI
分类号 A61K;A61K31/55;A61P25/18 主分类号 A61K
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