| 摘要 |
An isatin derivative represented by the general formula: <CHEM> wherein R<1> represents a hydrogen atom, an alkyl group, an aryl group, an aralkyl group or a cycloalkyl group, R<2> represents a branched-chain alkyl group, R<3> represents a hydrogen atom, an alkyl group, an aralkyl group or a cycloalkyl group, R represents a halogen atom, an alkyl group, an alkoxy group, an amino group, an acylamino group or an alkoxycarbonyl group, n is an integer of from 0 to 2, and Y represents an alkylene group; or a pharmaceutically acceptable salt thereof. The isatin derivatives and the pharmaceutically acceptable salts thereof possess anti-ulcer activities and thus are useful for prophylaxis and treatment of ulcer diseases in the digestive tract. |
