MONOCLONAL ANTI-ORNITHINE DECARBOXYLASE ANTIBODY AND METHOD OF PRODUCING SAME

摘要

of the Invention Monoclonal anti-ornithine decarboxylase antibody is produced by cell hybrids between hypoxanithine phosphoriboxyltransferase deficient myeloma cells and spleen cells derived from an animal previously immunized with ornithine decarboxylase. By means of immunoaffinity chromatography using cyanogen bromide-activated agsrose coupled with the antibody, ornithine decarboxylase in animal cell extracts can be highly purified in high yield.