发明名称 NOVEL ANTHELMINTIC FERMENTATION PRODUCTION OF BACTERIA
摘要 A novel microorganism ATCC-53110 is formed by the protoplast fusion of strains of Streptomyces avermitilis and Streptomyces hygroscopicus. A novel macrolide is isolated from the fermentation broth of this microorganism. The structure of the novel compounds isolated from the microorganism is presented based upon analytical studies. The compounds are highly potent antiparasitic, insecticidal, and anthelmintic agents, and may be made into suitable compositions for pharmaceutical, veterinary and agricultural use. The compounds have the formula: <CHEM> in which R1, R2 and R3 are defined as follows: <TABLE> f
申请公布号 JPS61267582(A) 申请公布日期 1986.11.27
申请号 JP19860101227 申请日期 1986.05.02
申请人 MERCK & CO INC 发明人 PAMERA EE MAKOOMITSUKU;ROBAATO TEE JIYOOJIRUMAN
分类号 A61K31/70;A01N43/90;A61K31/365;A61P33/10;C07D493/22;C07H19/01;C12P17/18;C12P19/44;C12P19/62;C12R1/465 主分类号 A61K31/70
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