摘要 |
NEW MATERIAL:A compound expressed by formula I (R<1> and R<2> are alkyl, cycloalkyl, lower alkenyl, lower alkynyl, aryl or aralkyl and both may be substituted by cyano, lower alkoxy, lower alkylthio, lower alkoxycarbonyl, etc., provided that R<1> and R<2> are not CH3 or C2H5 at the same time; Q is acid residue). EXAMPLE:N-(1, 3-dithiol-2-ylidene)-N-methyl-N-ethoxycarbonylmethylammonium perchlorate. USE:A medicine and remedy for hepatopathy, capable of exhibiting better remedial activity than malotilate expressed by formula II, and being an original hepatic function restorative agent or hepatic function stimulant for the reduction in substantial number of cells and function or the liver causing necrosis involving them, etc. PREPARATION:A dithiolium salt expressed by formula III (R is lower alkyl or aralkyl) is reacted with an amine expressed by formula IV in an inert solvent at -20 deg.C-the boiling point of the solvent to afford the aimed compound expressed by formula I.
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