| 发明名称 |
Substituted glutaric acid lactones in the treatment of hyperlipidemia |
| 摘要 |
Compounds of formula I <IMAGE> are described which are useful to inhibit the formation of serum cholesterol by virtue of their ability to inhibit beta -hydroxy- beta -methylglutaryl-CoA(HMG CoA), the rate-controlling substance in the synthesis of serum cholesterol.
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| 申请公布号 |
US4622338(A) |
申请公布日期 |
1986.11.11 |
| 申请号 |
US19850710375 |
申请日期 |
1985.03.11 |
| 申请人 |
G. D. SEARLE & CO. |
发明人 |
BARAN, JOHN S.;LINDBERG, THOMAS J.;LOWRIE, HARMAN S. |
| 分类号 |
A61K31/365;A61K31/366;A61P3/06;C07C27/00;C07C33/02;C07C33/14;C07C33/30;C07C67/00;C07C69/025;C07C69/66;C07D309/30;(IPC1-7):A61K31/365 |
主分类号 |
A61K31/365 |
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