| 摘要 |
<p>A monoclonal antibody specific for an a,-acid glycoprotein or for at least one antigenic determinant included in a sugar chain of the following formula:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="53" wi="87" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein Gal means galactose, GlcNAc means N-acetylglucos-amine, Man means mannose, Fuc means fucose, and n is 0 or 1, which is useful for the measurement of glycoproteins in cells, tissues and blood and therefore is useful for diagnosis of various diseases, particularly tumors, and a method for the production thereof by fusing a neoplasm cell line with antibody-producing cells from an animal which has been immunized against an de- sialated glycoprotein and culturing the resultant hybridoma.</p> |
