| 摘要 |
Carboxamides of formula(I) were prepd. by the hydrolysis of II. In (I) X is H, F, Cl, Br, C1-4 alkyl, C3-7 cycloalkyl, C1-4 alkoxy, C1-4 alkylthio, CF3, C1-4 alkylsulphinyl, C1-4 alkylsulphonyl, NO2, Ph, C2-4alkanoyl, benzoyl, thenoyl, C2-4alkanamido, or N,N-di(C1-3 alkyl) sulphamoyl; Y is H, F, Cl, Br, C1-4 alkyl, C3-7 cycloalkyl, or CF3 or X and Y together are 4,5-5,6- or 6,7methylenedioxy, or X and Y form Z which is gp. (III)-(VII); W is O or S; R is H or COR1; R1 is C1-6 alkyl, substd. Ph; n is 0,1 or 2; Q is divalent gp. divided from fran, pyrrol or benzothiophene; R is H or C1-3 alkyl I are inters for analgesic and antiinflammatory agents.
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