| 摘要 |
<p>This invention refers to the novel 184 amino acid sequence of a human natural inhibitor of collagenases (NIC) and its production. It also refers to novel DNA and RNA sequences, plasmids, transformed prokaryotic and eukaryotic cells, the production of NIC amino acid sequences with and without glycosylation, and compositions containing these novel NICs to treat diseases that incorporate collagenase-type metalloproteinases as part of the disease process.</p> |
