发明名称 |
Thiazolidine derivatives, process for the preparation and pharmaceutical compositions thereof |
摘要 |
New thiazolidine compounds of the formula (I) having anti-ulcer activity are disclosed: <IMAGE> (I) wherein Ar is a 2-furyl or a phenyl, naphthyl or pyridyl group optionally substituted by one or more C1-4-alkyl, C1-4-alkoxy, halo-C1-4-alkoxy, dihalomethyl, trihalomethyl, hydroxyl or nitro groups or by a group of the formula (II), <IMAGE> (II) wherein Y is nitrogen or CH; Z is cyano or carbamoyl if Y is nitrogen, and represents a nitro group if Y is CH. Also disclosed are several processes for preparing the new compounds as well as pharmaceutical compositions and method of treatment employing same.
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申请公布号 |
US4616025(A) |
申请公布日期 |
1986.10.07 |
申请号 |
US19840590486 |
申请日期 |
1984.03.16 |
申请人 |
RICHTER GEDEON VEGYESZETI GYAR RT |
发明人 |
EZER, ELEMER;HARSANYI, KALMAN;DOMANY, GYOERGY;SZPORNY, LASZLO;MATUZ, JUDIT;HEGEDUES, BELA;PALLAGI, KATALIN;SZABADKAI, ISTVAN;TETENYI, PETER |
分类号 |
A61K31/425;A61K31/426;A61K31/427;A61P1/04;C07D277/10;C07D277/18;C07D307/52;C07D417/06;C07D417/14;(IPC1-7):C07D277/10 |
主分类号 |
A61K31/425 |
代理机构 |
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代理人 |
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地址 |
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