发明名称 Thiazolidine derivatives, process for the preparation and pharmaceutical compositions thereof
摘要 New thiazolidine compounds of the formula (I) having anti-ulcer activity are disclosed: <IMAGE> (I) wherein Ar is a 2-furyl or a phenyl, naphthyl or pyridyl group optionally substituted by one or more C1-4-alkyl, C1-4-alkoxy, halo-C1-4-alkoxy, dihalomethyl, trihalomethyl, hydroxyl or nitro groups or by a group of the formula (II), <IMAGE> (II) wherein Y is nitrogen or CH; Z is cyano or carbamoyl if Y is nitrogen, and represents a nitro group if Y is CH. Also disclosed are several processes for preparing the new compounds as well as pharmaceutical compositions and method of treatment employing same.
申请公布号 US4616025(A) 申请公布日期 1986.10.07
申请号 US19840590486 申请日期 1984.03.16
申请人 RICHTER GEDEON VEGYESZETI GYAR RT 发明人 EZER, ELEMER;HARSANYI, KALMAN;DOMANY, GYOERGY;SZPORNY, LASZLO;MATUZ, JUDIT;HEGEDUES, BELA;PALLAGI, KATALIN;SZABADKAI, ISTVAN;TETENYI, PETER
分类号 A61K31/425;A61K31/426;A61K31/427;A61P1/04;C07D277/10;C07D277/18;C07D307/52;C07D417/06;C07D417/14;(IPC1-7):C07D277/10 主分类号 A61K31/425
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