发明名称 THIOBENZANILIDE OXIDE DERIVATIVE AND PRODUCTION THEREOF
摘要 NEW MATERIAL:A compound shown by the formula I (X is halogen; R is lower alkyl). EXAMPLE:N-(4-Chloro-2-methyl)phenylthiobenzamido-S-oxide. USE:A cardiac having anticonvulsant actioin, low toxicity and side effects. PREPARATION:A compound shown by the formula II is reacted with an organic peracid such as aqueous solution of hydrogen peroxide, perbenzoic acid, peracetic acid, etc., at room temperature for 20min-1hr, to give a compound shown by the formula I.
申请公布号 JPS61212557(A) 申请公布日期 1986.09.20
申请号 JP19850052034 申请日期 1985.03.15
申请人 NIPPON SODA CO LTD 发明人 TAKIGUCHI DAIGAKU;SATO TAKEHIRO;IGURA KATSUYATA
分类号 A61K31/165;A61P9/04;A61P25/08;C07C67/00;C07C325/00;C07C381/00 主分类号 A61K31/165
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