Ursodesoxycholic acid di:hemi:succinate - for treatment of biliary calculi and other biliary disorders

摘要

Ursodesoxy cholic acid dihemisuccinate (I) and its salts with alkali(ne earth) metals and basic amino acids, are new. - (II) is treated with succinic anhydride under anhydrous conditions in the presence of an acid acceptor. (I) may be given orally or parenterally at a daily dosage of 100-1000 mg.