| 摘要 |
PURPOSE:To provide a carcinostatic agent containing adriamycin and a specific compound as active components, having excellent carcino-static activity and exhibiting high drug action against the cancer cell having drug resistance. CONSTITUTION:The objective agent contains adriamycin and N-solanesyl-N,N'- bis(3,4-dimethoxybenzyl)ethylenediamine of formula as active components. Preferable daily dose is about 4mg-2g/kg for the compound of formula or its salt, and is about 10mg-2g/kg by oral administration and about 4mg-1g/kg for parenteral administration. The content of the active drug component depends upon the method of administration, and is >=1wt%, preferably 5-50wt%.
|
