NOVEL RETINOIC ACID DERIVATIVE, MANUFACTURE, MEDICINAL COMPOSITION AND COSMETIC COMPOSITION

摘要

The invention provides compounds of formula <IMAGE> (IV) in which formula R1 and R2 are identical or different and denote: (1) taken separately: a hydrogen atom, a linear or branched C1-C4 alkyl radical, an unsubstituted phenyl radical or a phenyl radical substituted with a halogen atom, with a C1-C4 alkoxy radical or with a C1-C4 alkoxy radical; (2) taken together either (a) a polymethylene linkage; or (b) a benzene ring; or (c) a cyclic linkage containing a nitrogen atom to constitute an isothiazolopyridinone derivative; m being able to have the values 0 or 1; the group A in the formula (IV) denoting the group <IMAGE> where R8 corresponds to a hydrogen atom, a methyl radical, a hydroxymethyl radical or a -CH2O-CO-Ret group. The invention also provides a process for preparing the abovementioned compounds and also drug compositions and cosmetic compositions containing them.