摘要 |
NEW MATERIAL:A compound expressed by formula I (R0 is H or methoxy; R1 is acyl; COOR is COOH which may be protected; X is halogen). EXAMPLE:Benzhydryl 7-(2-thienylacetamido)-3-carbamoyloxymethyl-3-cephem-4- carb-oxylate. USE:A disinfectant and remedy for infectious diseases. PREPARATION:A compound expressed by formula II (R1 is H or acyl), e.g. benzhydryl 7-(2-thienylacetamido)deacetylcephalosporanate, is reacted with a monohalogenoacetyl isocyanate, e.g. chloroacetyl isocyanate.
|