METHOD FOR THE ENZYMATIC CONVERSION OF A WATER- INSOLUBLE OR SUBSTANTIALLY WATER-INSOLUBLE ORGANIC SUBSTRATE

摘要

The invention relates to a method of converting a water-insoluble or substantially water-insoluble organic substrate under the influence of a water-soluble enzyme requiring a cofactor. The conversion is carried out in a micellar system, comprising an organic solvent which is not or substantially not water-miscible and in which the enzyme is solubilized via reversed micelles, stabilized by one or more surfactants, while the cofactor is regenerated in situ by means of one or more second enzymes also solubilized via reversed micelles in the organic solvent.