发明名称 |
Lipoprotein fractionation |
摘要 |
A process is described for removing low density and very low density lipoproteins from blood plasma or serum and recovering the plasma or serum in a physiologically acceptable form. The method involves in a preferred embodiment passing plasma or serum through a cationic ion exchanger equilibrated with a physiologically acceptable saline solution. The ion exchanger is a water insoluble hydrophilic, water swellable cross-linked regenerated or microgranular cellulose matrix substituted with hydroxy C2-C4 alkyl group. The ion exchanger capacity is provided by sulphate groups substituted with from 2 to 6 meq/g. The take up of low density lipoproteins is enhanced by recycling the plasma through the column.
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申请公布号 |
US4603010(A) |
申请公布日期 |
1986.07.29 |
申请号 |
US19850736306 |
申请日期 |
1985.05.21 |
申请人 |
AYERS, JOHN S.;HANCOCK, WILLIAM S.;HARDING, DAVID R. K. |
发明人 |
AYERS, JOHN S.;HANCOCK, WILLIAM S.;HARDING, DAVID R. K. |
分类号 |
C07K14/00;A61K35/14;A61K35/16;A61K38/16;A61M1/36;B01J39/04;B01J47/00;(IPC1-7):C07K15/16 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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