发明名称 PROCESS FOR PREPARING ANTI ULCER 2-GUANIDINO-4-(2-SUBSTITUTED-AMINO-4-IMIDAZOLIL)-THIAZOLES
摘要 New pharmaceutically active cpds. have formula (I), (R is NHR' or NR2; R' is 7 - 12C alkyl, 6 - 11C pyridylalkyl or 11 12C Ph-alkyl possibly mono- or disubstd. on the Ph with F, Cl, Br, 1 - 3C alkoxy or CF3; each R can independently be 1 - 12C alkyl or 7 - 12C Ph-alkyl opt. substd. on the Ph with F, Cl, Br, 1 - 3C alkyl or alkoxy or CF3; the 2R together with the N can form a pyrrolidone, piperidine, perhydro-1H-azepine or morpholine ring). (I) has an antisecretary action and can be used to prevent or treat gastric ulcers.
申请公布号 KR860000931(B1) 申请公布日期 1986.07.19
申请号 KR19830001962 申请日期 1983.05.09
申请人 PFIZER INC. 发明人 LAMATTINA JOHN LAWRENCE;LIPINSKI CHRISTOPHER ANDREW
分类号 C07D233/64;A61K31/425;A61K31/427;A61K31/44;A61P1/04;A61P43/00;C07D233/88;C07D263/48;C07D401/12;C07D413/04;C07D413/14;C07D417/04;C07D417/14;(IPC1-7):C07D413/04 主分类号 C07D233/64
代理机构 代理人
主权项
地址