发明名称 |
Stabilized bacampicillin hydrochloride, process for the stabilization and pharmaceutical compositions. |
摘要 |
<p>A new process for the stabilization of bacampicillin hydrochloride against degradation by humidity characterized by the incorporation of between 3 to 9% by weight of straight-chain alkanes, alkenes, fatty acids, alcohols, and esters of fatty acids and alcohols with molecular weights between 144 and 350, which may be carried out in one step together with wetmassing for granulation. Stabilized bacampicillin hydrochloride and pharmaceutical compositions are also disclosed.</p> |
申请公布号 |
EP0187626(A1) |
申请公布日期 |
1986.07.16 |
申请号 |
EP19850850351 |
申请日期 |
1985.10.31 |
申请人 |
ASTRA LAEKEMEDEL AKTIEBOLAG |
发明人 |
KJELLBERG, ULF ANDERS;NYQVIST, PER GUSTAF HAKAN;STENHEDE, JAN URBAN;STENMARK, LARS BERTIL |
分类号 |
A61K31/43;A61K9/16;C07D499/00;C07D499/32;C07D499/46;C07D499/68;(IPC1-7):A61K31/43;C07D499/64 |
主分类号 |
A61K31/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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