摘要 |
PURPOSE:To obtain a filler which provides a large strength and a high separation performance with an even mesh structure, by making polymer particles mainly composed of glycidyl monovinyl ester or glycidyl monovinyl ether hydrophylic by opening rings of epoxy groups after swelled in a proper solvent. CONSTITUTION:Glycidyl monovinyl ester or glycidyl monovinyl ether is used as main component and is polymerized in suspension with a proper amount of divinyl benzen or the like to introduce a desired crosslinked bond in addition to other copolymerizable monomers as required to obtain a polymer particle with the average particle size of 5-500mum. This particle is swelled in an organic solvent for swelling, such as aceton, and dioxane and made to react with polyvalent alcohol, amine or the like able to impart a hydrophylic group by opening the rings of epoxy groups to obtain a filler for a high performance liquid chromatography which is ideal for separation of a desired component with an excellent mechanical strength. This also can be utilized for industrial applications by massive filling thereof into a huge column. |