| 摘要 |
PURPOSE:To provide an antitumor agent containing a specific compound including known substance having sufficiently ascertained safety, exhibiting the effect to decrease the number of tumor cells, improve the life prolongation rate and suppress the proliferation of the tumor cell, and effective to animal or human tumor. CONSTITUTION:The objective agent contains the compound of formula I (R is H, CH3 or OCH3) or its salt, preferably 6-chloro-5-cyclohexyl-1- indanecarboxylic acid of formula II (R is H) as an active component. The active component is used singly or as a mixture with pharmacologically permissible carrier or adjuvant, and administered orally in the form of powder, tablet, capsule, etc. including sublingual administration, or parenterally in the form of injection in ampule, etc., suppository, ointment, etc. by injection, rectal infusion, etc. or dermal application. The content of the active component in the medicinal drug is 0.1-100wt%, and the component is administered at a dose of 0.1-1,000mg/kg daily for human optionally in 2-4 divided doses.
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