| 摘要 |
<p>Monoclonal antibodies specific for Enterobacteriaceae endotoxin are provided for passive immunization against Gram-negative bacterial sepsis. Particularly, by employing the core of J5 endotoxin as an immunogen, monoclonal antibodies are obtained specific for a broad range of endotoxins which can provide protection by passive immunization to a mammalian host, particularly a human host. The hybridoma D10 was deposited at the A.T.C.C. on November 8, 1983 and given Accession No. HB 8417, where D10 is a subclone from the fusion with X63-Ag8.653.</p> |
