| 摘要 |
A compound of the general formul: <IMAGE> wherein alpha beta means a saturated bond or a double bond; each R independently of one another is a methyl group or a methoxy group, or two R's taken together represent a group of -CH=CH-CH=CH-; n is zero or an integer of 1 through 9; when alpha beta is a saturated bond, R2 is a hydrogen atom or hydroxyl group, and when alpha beta is a double bond, R2 is a hydrogen atom; when alpha beta is a double bond or when R2 is a hydroxyl group, R1 is a carboxyl group, a group of CH22mOH (wherein m is an integer of 1 through 3) or a group of <IMAGE> (wherein m is an integer of 1 through 3); when alpha beta is a saturated bond and R2 is a hydrogen atom, R1 is a hydroxymethyl group or a group of <IMAGE> (wherein m is an integer of 1 through 3) has pharmacological actions such as membrane stabilizing activity (e.g. lysosomal membrane stabilizing activity), mitochondrial electron transport activity, hypotensive activity, activity to inhibit cardiac hypertrophy, tracheal muscle relaxant activity, cerebral circulation improving activity and cerebral ischemia preventive activity and is of value in the prophylaxis and treatment of hypertension, cardiac failure, asthma, cerebral apoplexy and other diseases, as a cardiac failure remedy, bronchodilator, cerebral circulation improving agent or the like. |
