| 摘要 |
PURPOSE:To obtain the titled substance economically in high yield, by using a mixture of an alcohol and other organic solvent as a reaction solvent, in contacting a 2-halogenocycloalkanone compound with an alkali metal hydroxide. CONSTITUTION:The titled compound can be produced by reacting a 2- halogenocycloalkanone compound (e.g. 2-chlorocyclohexane) with anhydrous alkali metal hydroxide in a mixture of an alcoholic solvent and other organic solvent (preferably a hydro-carbon such as benzene, xylene, hexane, etc.) at 10-150 deg.C, preferably 40-120 deg.C under atmospheric pressure. The amount of the alkali metal hydroxide is preferably 2-4 equivalent based on the above raw material. The amount of the mixed solventis usually 0.5-20pts.wt. per 1pt. of the raw materal, and the ratio of the alcohol to the other organic solvent is 50-97wt% to 3-50wt%.
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