| 摘要 |
PURPOSE:To produce the titled compound useful as an intermediate of agricultural and pharmaceutical chemicals, etc., in high yield, without producing by- products, by using 1,6-hexanediol as an easily available inexpensive raw material, and reacting the diol with hydrogen iodide, etc., and then with a cyaniding agent. CONSTITUTION:Suberonitrile is produced by reacting 1,6-hexanediol with hydrogen iodide or an alkali metal iodide (e.g. sodium iodide), and reacting the resultant 1,6-diiodohexane with a cyaniding agent (e.g. sodium cyanide, potassium cyanide, etc.). The 1,6-hexanediol used as the starting compound is obtained e.g. by the catalytic reduction of diethyl adipate or dimethyl adipate in the presence of sodium and an alcohol, or copper and a chromic acid compound. The reaction of said cyaniding agent with the diiodohexane proceeds under mild condition without necessitating a catalyst.
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