| 摘要 |
NEW MATERIAL:The 2-alkylthio-5-trifluoromethyl-6-disubstituted amino-3,4-di hydro-4 (3H) oxopyrimidine of formula I (R is alkyl; NR2' is secondary amine residue). USE:Pharmaceutical having physiological activity, and chemical intermediate. PREPARATION:The pyrimidine derivative of formula I can be prepared by reacting N-[(2-trifluoromethyl)-3,3,3-trifluoropropanoyl]-S-alkyliso-thiourea of formula II with a secondary amine.
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