| 摘要 |
NEW MATERIAL:A lymphokine II (molecular weight, 20,000+ or -2,000; isoelectric point, pI=6.2+ or -0.3; mobility, Rf=0.29+ or -0.02 by Disc-PAGE; solubility, soluble in water, saline water and phosphate buffer solution, hardly soluble or insoluble in ethyl ether, etc.; color reactions, positive to protein by Lawry reaction and micro-biuret reaction, positive to glucide by phenol sulfuric acid method; stability, stable at 60 deg.C for 30min at 7.2pH, stable at 4.0-11.0pH at 4 deg.C for 16hr, and stable for >=1 month in frozen state at -10 deg.C). USE:Agent for suppressing the proliferation of various malignant tumor cells. PREPARATION:The novel lymphokine II is produced by the cell prepared by transplanting a human-originated cell capable of producing the novel lymphokine II (e.g. leukocyte, lymphocyte, etc.) to a warm-blooded animal other than human, or by the cell proliferated under the supply of the body fluid of said warm- blooded animal. The lymphokine is essentially harmless to the normal human cell. |
