发明名称 |
Process for the optical resolution of racemic mixtures of alpha-naphtyl-propionic acids. |
摘要 |
<p>A new process for the optical resolution of racemic mixtures of alpha -naphthyl-propionic acids of formula
<CHEM>
where R1 is an alkyl group, straight or branched, having from 1 to 6 carbon atoms and R2 represents an hydrogen or an halogen atom.
<??>This process comprises reacting a racemic mixture of a compound of formula II
<CHEM>
wherein R1 and R2 have the above seen meanings and R3 is a reactive group, with an optically active compound of formula
R4-NH2 III
wherein R4 is the residue of a primary or secondary alcohol which, taken with the NH2 radical, forms an optically active beta -aminoalcohol, to give a pair of diastereoisomeric amides of </p> |
申请公布号 |
EP0182279(A1) |
申请公布日期 |
1986.05.28 |
申请号 |
EP19850114450 |
申请日期 |
1985.11.13 |
申请人 |
ALFA CHEMICALS ITALIANA S.P.A. |
发明人 |
CANNATA, VINCENZO;TAMERLANI, GIANCARLO |
分类号 |
C07C51/06;C07B57/00;C07B31/00;C07C51/00;C07C51/487;C07C57/38;C07C59/64;C07C67/00;C07C231/00;C07C231/02;C07C231/12;C07C231/20;C07C235/08;C07C235/34;(IPC1-7):C07C59/64;C07C103/78 |
主分类号 |
C07C51/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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