STABILISATION PAR COMPLEXATION ET LYOPHILISATION DE METABOLITES INTERMEDIAIRES SENSIBLES ET BIOLOGIQUEMENT ACTIFS, COMPLEXES OBTENUS ET LEURS UTILISATIONS

摘要

A sensitive intermediate metabolite such as a folic acid derivative or analog is stabilized by complexing it with a complementary binder or receptor such as a protein and then lyophilizing the complex. An example of such a folic acid derivative is N-5-methyltetrahydrofolic acid.