摘要 |
A mechanism for filling containers within a sterile chamber under aseptic conditions includes a nozzle (48) which forms an extension of the sterile chamber and which is arranged to have a lower outlet end inserted into an open container to be filled and which is provided with valve closure element (51) which is opened when the nozzle is at its lowermost position and which remains open during filling of the container. Filling is accompanied by upward movement of the nozzle and of the closure element while maintained in open position so as to prevent splashing together with a seal (49, 52 and 53) for preventing dripping following closure of the valve means. The fluid is isolated from atmosphere by suitable barrier cavities containing sterile inert gas under slight pressure above atmospheric pressure and defined in part by rolling seals which isolate the moving elements from atmosphere. |