发明名称 N2-ARILSOLFONIL-L-ARGININAMMIDI E LORO SALI ACCETTABILI DAL PUNTO DI VISTA FARMACEUTICO
摘要 <p>The arginamides correspond to the formula: <IMAGE> in which Ar represents various aromatic groups and R represents one of the following groups: <IMAGE> The detailed definition of the Ar groups and the symbols in the R groups is found in Claim 1. The compounds and their acid addition salts are prepared from L-arginine by a three-step process. They have a specific inhibitory action against thrombin and can be used, preferably in the form of pharmaceutical preparations, for the treatment and for the prophylaxis of thromboses.</p>
申请公布号 IT1126229(B) 申请公布日期 1986.05.14
申请号 IT19770031297 申请日期 1977.12.27
申请人 MITSUBISHI CHEMICAL INDUSTRIES LTD;SHOSUKE OKAMOTO 发明人 OKAMOTO SHOSUKE;KIKUMOTO RYOJI;TAMAO YOSHIKUNI;OHKUBO KAZUO;TEZUKA TOHRU;TONMURA SHINJI;HIJIKATA AKIKO
分类号 C07C311/18;A61K38/00;C07C311/19;C07D209/44;C07D211/16;C07D211/32;C07D211/34;C07D223/06;C07D225/02;C07D265/30;C07D295/185;C07D307/14;C07D307/52;C07D309/04;C07D311/14;C07D319/18;C07D319/22;C07D327/08;C07D333/76;C07D405/12;C07K5/072;(IPC1-7):A61K/ 主分类号 C07C311/18
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