发明名称 |
NOVEL PIPERAZINE DERIVATIVES PROCESSES FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID COMPOUNDS AS ACTIVE INGREDIENT |
摘要 |
<p>A 1-benzhydryl-4-cinnamylpiperazine derivative represented by the following formula (I) <IMAGE> (I) wherein R1 represents a hydrogen atom or a methoxy group, and R2 represents a hydrogen or fluorine atom, or a pharmaceutically acceptable acid addition salt thereof. The compound (I) is prepared by selectively reducing the corresponding 1-benzhydryl-4-cinnamoylpiperazine derivative and optionally converting the product into its acid addition salt. The compound (I) is useful for treatment of cerebrovascular disease in a human.</p> |
申请公布号 |
GR860045(B) |
申请公布日期 |
1986.05.12 |
申请号 |
GR19860100045 |
申请日期 |
1986.01.09 |
申请人 |
KANEBO LTD |
发明人 |
OHTAKA HIROSHI;KANAZAWA TOSHIRO;ITO KEIZO;TSUKAMOTO GORO |
分类号 |
C07D295/08;A61K31/495;A61P9/00;C07D295/096 |
主分类号 |
C07D295/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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