摘要 |
The formulation has a solid active ingredient in admixture with a particulate microporous polymer prepared from a homogeneous solution of a synthetic thermoplastic polymer in a compatible liquid, the solution having been cooled at a rate and to a temperature sufficient to initiate thermodynamic non-equilibrium liquid-liquid phase separation and to form a microporous solid from which liquid is then removed. Preferred active ingredients are antibiotics, analgesics, anti-inflammatories, CNS drugs, growth hormones etc. The formulations may be administered, orally, topically parenterally or can be injected as suspensions or implanted. |