发明名称 |
N-oleyl-phosphatidyl-ethanolamine derivs. - with anti:arteriosclerotic and antilipaemic activity, prepd. by reacting n-substd. phospholipid with oleic acid chloride or anhydride |
摘要 |
<p>New phosphatidylethanolamine N-oleyl derivs. are of formula (I): In (I), R1 and R2 are the residues of 12-22C fatty acids (pref. natural) which may be satd. or unsatd. (contg. >=1 double bonds) and be branched or unbranched. (I) have anti-arteriosclerotic and antilipaemic activity after oral admin. In experiments in rats, 1 mg./kg. gives marked lowering of total lipids, esp. cholesterol and triglycerides, in serum.</p> |
申请公布号 |
IT1121798(B) |
申请公布日期 |
1986.04.23 |
申请号 |
IT19790023539 |
申请日期 |
1979.06.13 |
申请人 |
A. NATTERMANN & CIE. GMBH |
发明人 |
DAWIDSON HERBERT;BETZING HANS |
分类号 |
A61K;(IPC1-7):A61K/ |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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