CHEMICALLY MODIFIED SURFACE FOR LARGE MOLECULE ATTACHMENT

摘要

The attachment and/or orientation of biologically active large molecules can be controlled by varying the surface chemistry of a substrate in contact with the large molecule. The surface chemistry of polymeric surfaces can be varied by using selected homopolymers, copolymerization, surface grafting, chemical modification and plasma treatment of the surface. In particular, plasma modification processes may be used to provide specific chemical functional groups, element ratios and other surface properties.