发明名称 ALPHA-(N-PYRROLYL)-PHENYLACETIC ACIDS ESTERS THEREOF THEIR PREPARATION PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THERAPEUTICAL APPLICATIONS THEREOF
摘要 <p>A process for the preparation of alpha-(N-pyrrolyl)-derivative acids, the salts and esters thereof, of the formula <IMAGE> in which R, R1, R2, R3 and R4 are hydrogen atoms or substituted or unsubstituted alkyl, aryl, alkylaryl or heterocyclic radicals and R' is a metal cation, an organic base or an organic radical, wherein the corresponding amino ester is reacted with a dialkoxytetrahydrofuran or a derivative thereof. Certain compounds comprised among those corresponding to the above formula, particularly the DL, D and L-alpha-(N-pyrrolyl)-phenylacetic acids and certain esters thereof. Therapeutical compositions containing such compounds as active ingredient and therapeutical applications of said compounds.</p>
申请公布号 GB2122189(B) 申请公布日期 1986.04.16
申请号 GB19830012804 申请日期 1983.05.10
申请人 * ANTIBIOTICOS SA 发明人 FRANCISCO SALTO * MALDONADO;LUIS COSTA * PLA;JOSE LUIS FERNANDEZ * PUENTES;JOSE MARIA FERNANDEZ * SOUSA-FARO
分类号 A61K31/40;A61P7/02;A61P25/04;C07D207/32;C07D207/327;(IPC1-7):C07D207/327 主分类号 A61K31/40
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