发明名称 Process for preparing hydroxyalkylaminosulfonic acids
摘要 A process for preparing hydroxyalkylaminosulfonic acids which comprises reacting a hydroxyalkylamine of the formula: <IMAGE> (II) wherein R1 is a C1-C20 hydroxyalkyl group optionally containing -O- or -COO- in the alkyl chain, and R2 is a hydrogen atom, a C1-C20 hydroxyalkyl group optionally containing -O- or -COO- in the alkyl chain, or a lower alkyl group, with an alkali metal salt of an alpha , beta -unsaturated sulfonic acid of the formula: <IMAGE> (III) wherein R3 is a hydrogen atom or a methyl group and M is an alkali metal, followed by elimination of the alkali metal to give a hydroxyalkylaminosulfonic acid of the formula: <IMAGE> (I) wherein R1 and R3 are each as defined above and R2' is a hydrogen atom, a C1-C20 hydroxyalkyl group optionally containing -O- or -COO- in the alkyl chain, a lower alkyl group or a group of the formula: <IMAGE> wherein R3 is as defined above.
申请公布号 US4582651(A) 申请公布日期 1986.04.15
申请号 US19840599823 申请日期 1984.04.13
申请人 NIPPON PAINT CO., LTD. 发明人 ISHII, KEIZOU;MIZUGUCHI, RYUZO;ISHIKURA, SHINICHI;YOSHIOKA, TAMOTSU
分类号 A61K31/38;A61K31/40;A61K31/415;C07D207/16;C07D231/06;(IPC1-7):C07C143/02;C07C101/30 主分类号 A61K31/38
代理机构 代理人
主权项
地址