摘要 |
A totally porous activated gel which comprises a matrix of a totally porous crosslinked copolymer comprising as main components vinyl alcohol monomer units and crosslinkable monomer units and having a specific surface area of 5 to 1000 m2/g and an reactive group linked to said matrix by a covalent bond. The present activated gel is very useful for effectively separating bio-substances due to the peculiar behavior of the reactive group of the activated gel. The activated gel is rigid, and is excellent in mechanical strength, resistance to chemicals, high pH, low pH, high temperature and low temperature, and is very effective in specific adsorption of bio-substances. The activated gel can be subjected to freeze-drying sterilization, heat sterilization and radiation sterilization, so that it can be utilized for the medical treatment by extracorporeal perfusion of, for example, blood. |