摘要 |
Non-thrombogenic materials prepared by reacting a heparin-type anticoagulant, hydroxyl, or combinations of hydroxyl and acetal groups that are part of already synthesized macromolecules having an atomic carbon-to-oxygen ratio in excess of unity, an aldehyde and an acid catalyst. The non-thrombogenic materials can be used for implanted and extracorporeal biomedical devices and prostheses intended to be used in direct contact with blood, including tubes, valves, membrane assemblies for blood dialysis and oxygenation, anesthesia-carrying tubes, etc.
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