发明名称 |
METHODS FOR PREPARATION OF HEPATITIS B SURFACE ANTIGEN FREE GAMMA GLOBULINS AND PRODUCTS |
摘要 |
<p>Methods for producing from human serum, human gamma globulin essentially free of HBsAg and products resulting therefrom. Specifically provided are ion exchange resin/buffer systems capable of effectively removing HBsAg thought to be closely correlated with viral hepatitis type B infectivity. Additional steps can include ultrafiltration to increase reduction of any virus not removed in the column passage as well as the addition of anti-HBg to substantially eliminate all infectivity.</p> |
申请公布号 |
EP0102731(A3) |
申请公布日期 |
1986.03.26 |
申请号 |
EP19830304283 |
申请日期 |
1983.07.25 |
申请人 |
ORTHO DIAGNOSTIC SYSTEMS INC. |
发明人 |
ZOLTON, RAYMOND P.;KAPLAN, PAUL M.;PADVELSKIS, JOHN V. |
分类号 |
A61K39/395;A61K35/14;A61K39/29;B01D15/08;C07K16/00;C07K16/06;(IPC1-7):B01D15/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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