| 摘要 |
The manufacture of optically active bifunctional compounds of the general formula <IMAGE> I wherein R represents protected hydroxymethyl, protected formyl or alkoxycarbonyl and R1 represents a group of the formula <IMAGE> or -CH2-CH=NR2 in which R2 and R3 represent lower alkyl or cycloalkyl or R2 and R3 together with the nitrogen atom represent a heterocyclic ring, by isomerizing compounds of the general formula <IMAGE> II wherein R, R2 and R3 have the above significance and R3 can additionally signify hydrogen, is described. The compounds of formula I are potential intermediates in the manufacture of, inter alia, natural vitamin E and natural vitamin K1.
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