Thiazole derivatives and procedure of synthesis thereof

摘要

A series of new 2,4-substituted thiazole derivatives are disclosed. These compounds have anti-histaminergic activity, especially, outstanding gastric anti-secretory activity. The compounds of this invention are obtained mainly by reacting 2-substituted-4-aminoalkyl-thiomethyl thiazole with a compound having methylthio or hydroxy group corresponding thereto.