摘要 |
DIOXOPYRANOQUINOLINE DICARBOXYLIC ACID DERIVATIVES There are described compounds of formula I I in which an adjacent pair of R5, R6, R7 and R8 form a chain -COCH=CE-O-, and the remainder of R5, R6, R7 and R8, which may be the same or different, each represent hydrogen, hydroxy, alkyl, halogen, alkenyl, alkoxy, or -NR1R2 in which R1 and R2, which are the same or different, are each hydrogen or alkyl, Rg is hydrogen, alkyl, alkenyl or phenyl-alkyl, and E is -COOH, a 5-tetrazolyl group or an (N-tetra-5-yl) carboxamido group, and phrmaceutically acceptable derivatives thereof. There are also described processes for making the compounds and pharmaceutical, e.g. anti-allergic, compositions containing the compounds. |