发明名称 New 1-normon-2-yl-heterocyclic cpds.
摘要 <p>1-Normon-2-yl-heterocyclic cpds. of formula (I). Het = 5-membered heterocyclic ring having a 6-pi electron system and contg. (a) 1C + 4C and N; (b) 2C, 2N + 10 or S; or (c) 4C + 10 or S; R1 = substituent on a C or N atom and selected from 1-20C alkyl, 2-8C alkenyl, aryl, aralkyl or heterocyclyl each opt. substd., or H or 3-7C cycloalkyl; R2 = where approp. a substit. on a C or N atom and is a R1 substit. - Cpds. of formula (II) are also new and are intermediates. Z1-Z3 = H or protecting gps.; W = NHNHY, NHR'1 or ON:CR1-NH2; Y = H or COR1; R'1 = p-NO2-, m-CN- or p-MeSO2-phenyl.</p>
申请公布号 ES8601981(A1) 申请公布日期 1986.03.01
申请号 ES19990005386 申请日期 1984.12.17
申请人 BEECHAM GROUP P.L.C. 发明人
分类号 A61K31/41;A61K31/44;A61K31/443;A61K31/4433;A61P15/14;A61P31/00;A61P31/04;C07D405/06;C07D405/14;C07D407/06;C07D409/14;C07D413/06;C07D413/14;C07F7/18;(IPC1-7):C07D413/06;A61K31/35;A61K31/42 主分类号 A61K31/41
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