Phenethanolamine derivatives

摘要

Phenethanolamine derivatives are disclosed of formula wherein m is 2 to 8; n is 1 to 7 provided that m+n is 4 to 12; Ar is phenyl or phenyl substituted by one or two halogen atoms, alkyl or alkoxy groups or by an alkylenedioxy group; R<1> and R<2> are hydrogen or alkyl provided that the sum total of carbon atoms in R<1> and R<2> is not more than 4; and the physiologically acceptable salts and solvates thereof. Also disclosed as novel are compounds of formula Ar(CH2)nO(CH2)mX where X is -CH(R<2>)L, R<2>CO- or -C(R<1>)(R<2>) NHY<1>, where L is a leaving group and Y<1> is H or a group convertible thereto by catalytic hydrogenation.