发明名称 Synergistic non-steroidal anti-inflammatory compounds and compositions thereof
摘要 Non-steroidal anti-inflammatory compositions comprising a compound of the formula: <IMAGE> wherein R1 is H or OH; and X, Y, X1 and Y1 represent hydrogen or halogen, such as chloro, fluoro, bromo, or iodo radicals, lower alkyl radicals such as C1-C8 radicals, such as methyl, ethyl, propyl and butyl, lower haloalkyl radicals, such as trifluoro, trichloro or tribromo methyl radicals, and lower alkoxy radicals, such as C1-C8 radicals such as methoxy, ethoxy, propoxy, and octyloxy radicals or combinations thereof and the salts thereof, in combination with a compound selected from the group consisting of butylated hydroxytoluene, nordihydroguaiaretic acid and mixtures thereof, said combination being contained in a pharmaceutically acceptable carrier. A method of treating pain and inflammation is also disclosed.
申请公布号 US4568696(A) 申请公布日期 1986.02.04
申请号 US19850718270 申请日期 1985.04.01
申请人 WARNER-LAMBERT COMPANY 发明人 SMERBECK, RICHARD V.;PITTZ, EUGENE P.
分类号 A61K31/12;A61K31/335;A61K31/355;(IPC1-7):A61K31/05 主分类号 A61K31/12
代理机构 代理人
主权项
地址